Loosely defined, probiotics are ingested microbes that can modify intestinal microbial populations in a way that benefit the host. Many of the benefits of supplemental microflora, including Bifidobacteria and Lactobacilli, are well known. These benefits include maintenance of intestinal homeostasis, competitive exclusion of pathogens, production of antimicrobial compounds, promotion of the intestinal barrier function, immune modulation and some very promising results in the area of inflammatory bowel disease.1